2-(Piperazin-1-yl)pyridine-4-boronic acid, picol ester

2-(Piperazin-1-yl)pyridine-4-boronic acid, picol ester - Names and Identifiers

Name	2-(1-Piperazinyl)pyridine-4-boronic acid pinacol ester
Synonyms	2-(Piperazin-1-yl)pyridine-4-boronic acid 2-(1-Piperazinyl)pyridine-4-boronic acid pinacol ester 2-(Piperazin-1-yl)pyridine-4-boronic acid, picol ester (2-(PIPERAZIN-1-YL)PYRIDIN-4-YL)BORONIC ACID PINACOL ESTER 1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-yl)piperazine Piperazine, 1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]-
CAS	957198-31-1
InChI	InChI=1/C15H24BN3O2/c1-14(2)15(3,4)21-16(20-14)12-5-6-18-13(11-12)19-9-7-17-8-10-19/h5-6,11,17H,7-10H2,1-4H3

2-(Piperazin-1-yl)pyridine-4-boronic acid, picol ester - Physico-chemical Properties

Molecular Formula	C15H24BN3O2
Molar Mass	289.18
Density	1.11±0.1 g/cm3(Predicted)
Melting Point	112-116°C
Boling Point	458.5±40.0 °C(Predicted)
Flash Point	231.1°C
Vapor Presure	1.36E-08mmHg at 25°C
pKa	8.65±0.10(Predicted)
Storage Condition	Room Temprature
Refractive Index	1.542
MDL	MFCD06795687

2-(Piperazin-1-yl)pyridine-4-boronic acid, picol ester - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3

2-(Piperazin-1-yl)pyridine-4-boronic acid, picol ester - Introduction

2-(1-Piperazinyl)pyridine-4-boronic acid pinacol ester(2-(1-Piperazinyl)pyridine-4-boronic acid pinacol ester) is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: Colorless solid
-Molecular formula: C15H22BKN3O2
-Molecular weight: 321.17g/mol
-Solubility: Soluble in organic solvents such as chloroform, ethanol and dimethyl ketone
-Melting point/boiling point: limited information, usually not reported in the literature

Use:
- 2-(1-Piperazinyl)pyridine-4-boronic acid pinacol ester is an organoboron reagent, which is widely used in coordination chemistry and organic synthesis.
-It is often used to catalyze reductive coupling reactions, such as Suzuki-Miyaura reactions, to construct carbon-carbon bonds or carbon-boron bonds.
-The compound can also be used in pharmaceutical research and development, such as the design and synthesis of new drugs and the exploration of bioactive molecules.

Preparation Method:
The preparation method of -2-(1-Piperazinyl)pyridine-4-boronic acid pinacol ester is more complicated, and usually requires organic synthesis reactions.
-Specific synthesis methods can be referred to in accordance with specific literature or patents.

Safety Information:
- 2-(1-Piperazinyl) Security information pyridine-4-boronic acid pinacol ester is limited.
-During handling and use, care should be taken to avoid contact with skin, eyes and mucous membranes and to avoid inhaling dust.
-When using this compound, follow laboratory safety procedures and use personal protective equipment, such as gloves, goggles and laboratory coats, as appropriate.

Please note that the use and handling of organic compounds requires strict compliance with relevant laboratory practices and safety guidelines to ensure personal safety and laboratory safety.

Last Update：2024-04-09 19:05:53